Natural Science Corporation of America
  Migra-Lieve TM                     U.S. Patent and U.S. and World Patents Pending

A Dietary Supplement Supporting Cerebrovascular Tone*
Patent pending formula recommended and used by Neurologists, Internists, and Family Practitioners.

Migra-LieveTM is a unique combination of herbal and nutritional supplements aimed at supporting cerebrovascular tone, and reducing platelet aggregation and the production of pro-inflammatory mediators.* The herbal and nutritional ingredients in Migra-Lieve TM are used in the amounts shown to be beneficial in scientific studies.

Commonly recommended for its ability to support cerebrovascular tone, feverfew (Tanacetum parthenium) is rich in compounds known as sesquiterpene lactones. The most important of these compounds is parthenolide, which represents 85% of the sesquiterpene lactone content in feverfew leaf extracts. Particularly important in feverfew extracts is the parthenolide content as well as the stability of this important constituent. Migra-LieveTM is not only standardized to a high parthenolide content of 0.7% but also measures the stability of parthenolide. Standardization insures the optimal dosage of parthenolide in an extract that will not lose its potency over time. Scientific studies have found parthenolide inhibits platelet aggregation and the release of serotonin from platelets and polymorphonuclear leukocyte granules.* It has also been shown to inhibit pro-inflammatory prostaglandin synthesis and the release of arachadonic acid.*

European studies have shown the benefits of a feverfew extract, standardized on parthenolide content, on the long-term support of cerebrovascular tone.*

Magnesium is a nutritional supplement with numerous effects that support vascular tone.* These include: 1) inhibition of platelet aggregation;2) interference with synthesis, release, and action of inflammatory mediators;3) direct alterations of cerebrovascular tone; 4) inhibition of vasospasm; and 5) stabilization of cell membranes.* Some persons with poor cerebrovascular tone have been found to have low brain levels of magnesium.* Recommended daily dosages of magnesium typically range from 200 to 600 mg to compensate for this deficiency.*

Riboflavin (vitamin B-2) is a precursor of flavin adenine dinucleotide(FAD). This coenzyme is an important component of the electron-transport chain. A deficiency of mitrochondrial energy reserves has been observed in some persons exhibiting poor cerebrovascular tone. This defect may theoretically be corrected by a compound such as riboflavin that improves the activity of the electron-transport chain.*

INGREDIENTS - Two Caplets Provide: Amount% of U.S. RDA*

Feverfew (Tanacetum parthenium) Extract..........100 mg. (Standardized to 0.7% Parthenolide)
Maganesium (Citrate/Oxide 1:1)........................300 mg............................75
Riboflavin (Vitamin B-2)...................................400 mg............................23,525
*Percentage of U.S. Recommended Daily Allowance
Contains no yeast, milk, corn, wheat, gluten, soy sodium, salt, sugar,flavorings, preservatives, artificial colors.

- Take one caplet twice daily. Migra-LieveTM is designed to provide benefits within four to six weeks. Once results are noted, Migra-LieveTM may be used for several months as part of a daily supplement regime and comprehensive wellness program.

 Note: This information was obtained from the company's web site. It was accurate at the time, but if you want to check for accuracy, visit the company's web site, or contact them directly. PNS Partners is not responsible for any errors, omissions or changes.

PNS Partners, Inc. - 100 Park Ave, New York, NY 10017
© 2002 PNS Partners Inc. All rights reserved.